In the almost 300 years of its existence, the Baroque Palace has changed its name several times depending on the dominant policies and administrative reorganization of the city. It was built in stages, with the Main Square, Dom Square, today's Union Square [Piaţa Unirii]. The south side of the Square was chosen for the President's Palace, the land on which in 1733-1735 stood the Mining Office building and, next to it, the Military Cashier's Office. The construction of the Baroque Palace was started from these two buildings, which were joined by a superstructure. The facade of the Palace has a sumptuous Baroque decoration, alternating between two types of interlacing on the pilasters, parapets and window copings. In 1778, when Vienna decided to reorganize the region under the Hungarian Administrative Council, with the old districts becoming counties, the Baroque palace continued to play its role as the County House. Between 1849-1861 in the newly established autonomous region of Serbian Vojvodina and Timişan Banat, the Baroque Palace became the seat of the administration, which in that decade was directly subordinate to Vienna.

At the end of the 19th century, the Baroque Palace underwent a transformation to its present form. Restoration was carried out in 1885-1886 by Jakob-Jacques Klein (1855-1928), an architect and builder from Chernivtsi, who was responsible for the so-called “stylistic purification”. In an attempt to bring the image of the Baroque Palace closer to the French Neo-Renaissance style, the design included a rich decoration of ironwork, materialized by the two exterior iron gates. They were made in the form of griffins and flank the corners of the building facing the square. After the Second World War, the Baroque Palace housed the Faculty of Agronomy of the Timișoara Polytechnic, which later became the Banat University of Agronomy and Veterinary Medicine. Located in the historic centre of the city, in a square whose architecture is also marked by the baroque style, the Baroque Palace today houses the Timișoara Art Museum, a reference institution of contemporary cultural life.